Can Anti-Müllerian Hormone Levels Predict Menopause?
BACKGROUND AND PURPOSE:
Concentrations of hormones involved in ovulation can be used as markers to assess ovarian reserve.
This study by Kim et al. (Maturitas, 2017) sought to examine whether anti-Müllerian hormone (AMH) levels, follicle stimulating hormone (FSH) levels and antral follicle count (AFC) can be used to predict the start of menopause
Retrospective Cohort Study
426 women from the Coronary Artery Risk Development in Young Adults Study (CARDIA) were included
Mean age 43 years old at time of measurements
Serum measurements of AMH and FSH were taken, and the women underwent transvaginal ultrasounds
For women age 45-49 years old, menopause occurred within 5 years if
undetectable levels of AMH was associated with a >60% chance of menopause within 5 years
approximately 30% of women with one or no antral follicles began menopause within 5 years
Low and high concentrations of FSH were associated with increased chance of menopause compared to intermediate levels of the hormone
Age and a single marker were sufficient to predict onset of menopause
AMH, FSH, and AFC can all be used to predict menopause
Please sign up or log in to your ObGFirst to access this Premium Content
Media - Internet
Computer System Requirements
OBG Project CME requires a modern web browser (Internet Explorer 10+, Mozilla Firefox, Apple Safari, Google Chrome, Microsoft Edge). Certain educational activities may require additional software to view multimedia, presentation, or printable versions of their content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Apple QuickTime, Adobe Acrobat, Microsoft PowerPoint, Windows Media Player, or Real Networks Real One Player.
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Jointly provided by
NOT ENOUGH CME HOURS
It appears you don't have enough CME Hours to take this Post-Test. Feel free to buy additional CME hours or upgrade your current CME subscription plan