How Accurate are At-Home Screening Tests for High-Risk HPV and STDs?
BACKGROUND AND PURPOSE:
Des Marais et al. (Obstetrics & Gynecology, 2018) assessed the validity and acceptability of at-home self-collection kit to test for human papillomavirus (HPV) and STDs in women at higher risk as a result of underscreening for cervical cancer
2nd phase of My Body, My Test study
30–64 years of age | No history of Pap testing in the past 4 years | Household income below 250% of the poverty level | Not pregnant | No previous hysterectomy | Uninsured, underinsured, or on Medicaid
Participants provided cervicovaginal samples by one of 3 routes
Self-home (sample returned by mail)
Self-clinic (sample handed to nurse at visit)
Samples were tested for
High-risk HPV (14 high-risk HPV genotypes, with positive results reflexed for types 16 and for 18/45)
Cervical samples were also tested by liquid-based cytology
Primary outcome: Clinical performance of high-risk HPV testing on self-collected cervicovaginal samples vs clinician-collected samples for ≥CIN2
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presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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