What Are the Risk Factors for Age-Associated Muscle Strength Loss Following Menopause?
BACKGROUND AND PURPOSE:
García-Alfaro et al. (Menopause, 2022) evaluated the prevalence of dynapenia (age-related muscle strength loss) and related factors among postmenopausal women
50 to 84 years
Age at menopause
Adiposity (assessed by bioelectric impedance)
Physical activity level was evaluated by using the International Physical Activity Questionnaire
Bone mineral density was reported as T-scores
Blood biochemical parameters (calcium, phosphorus, vitamin D, and parathormone levels) were measured
Prevalence of dynapenia: 31.3%
Exposures associated with lower handgrip strength
Age ≥65 years: P<0.001
Menopause at <51 years: P=0.005
Fat content ≥40%: P<0.001
There was no statistically significant difference among handgrip strength with respect to
Plasma levels of vitamin D
Women were more likely to have dynapenia with
Every 1 year in age: Odds ratio (OR) 1.09 (95% CI, 1.04 to 1.14)
Each 1% increase in adiposity: OR 1.06 (95% CI, 1.00 to 1.13)
Women with higher femoral neck T-score were less likely to have dynapenia
OR 0.53 (95% CI, 0.35 to 0.78)
Low physical activity was associated with lower handgrip strength vs moderate-high physical activity (P = 0.027)
Risk factors for reduced handgrip strength post menopause were
Age at menopause
Low bone mineral density
The authors state
Handgrip strength is a standard test to evaluate muscle health status
Therefore, the routine implementation of grip strength measurement can be recommended for the study of changes in body composition and muscle strength under different treatments or physical activity programs in health care services
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