220 women with psoriasis | 298 pregnancies | Median follow-up duration 7.2 years | Biologic therapy exposure in 56.4% of pregnancies
Mean age at time of pregnancy outcome: 30.9 years
Past or current smokers: 55.0%
Spontaneous abortion: 13.8%
Elective termination: 4.4% (none associated with anomalies)
Gestational age at birth
Full term: 90.9%
Healthy newborns: 94.7%
Infants with a neonatal problem: 4.1% (3 respiratory issues, 2 preterm deliveries related to pre-eclampsia, and 1 of each of the following: ABO blood type mismatch, LBW, opioid withdrawal, hyperemesis, and hypoglycemia)
Congenital anomaly: 2 anomalies in one infant (small posterior cleft palate and unilateral craniosynostosis)
252 of 298 pregnancies were associated with biologic exposure before or during pregnancy
Pregnancy outcomes for women exposed to biologics were similar to those for women exposed to nonbiologics
Women with psoriasis, including those exposed to biologics, had pregnancy and live birth outcomes similar to the general population
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