Cochrane Reviews: Prophylaxis for Preventing Ophthalmia Neonatorum
BACKGROUND AND PURPOSE:
Kapoor et al. (Cochrane Systematic Reviews, 2020) sought to determine if pharmacologic prophylaxis is superior to placebo for the prevention of ophthalmia neonatorum, and if so, which is the preferred medication
Systematic review and meta-analysis
Aside from usual database searches and reference checks, the authors also contacted pharmaceutical companies
Randomized and quasi-randomized controlled trials
Studies that examined any topical, systemic, or combination medical interventions used to prevent ophthalmia neonatorum in newborns compared with placebo, no prophylaxis, or with each other
Study was conducted with standard Cochrane methods
Blindness or any adverse visual outcome at 12 months
Conjunctivitis at 1 month: Gonococcal (GC) | Chlamydial (CC) | Bacterial (BC) | Any etiology (ACAE) | Unknown etiology
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Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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