The Final USPSTF Recommendations on Pancreatic Cancer Screening
Learning Objectives and CME/Disclosure Information
This activity is intended for healthcare providers delivering care to women and their families.
After completing this activity, the participant should be better able to:
1. State the USPSTF recommendations on screening for pancreatic cancer in the general population 2. Discuss the risks and benefits of pancreatic screening in the general population
Estimated time to complete activity: 0.25 hours
Susan J. Gross, MD, FRCSC, FACOG, FACMG
President and CEO, The ObG Project
Disclosure of Conflicts of Interest
Postgraduate Institute for Medicine (PIM) requires faculty, planners, and others in control of educational content to disclose all their financial relationships with ineligible companies. All identified conflicts of interest (COI) are thoroughly vetted and mitigated according to PIM policy. PIM is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.
The PIM planners and others have nothing to disclose. The OBG Project planners and others have nothing to disclose.
Faculty: Susan J. Gross, MD, receives consulting fees from Cradle Genomics, and has financial interest in The ObG Project, Inc.
Planners and Managers: The PIM planners and managers, Trace Hutchison, PharmD, Samantha Mattiucci, PharmD, CHCP, Judi Smelker-Mitchek, MBA, MSN, RN, and Jan Schultz, MSN, RN, CHCP have nothing to disclose.
Method of Participation and Request for Credit
Fees for participating and receiving CME credit for this activity are as posted on The ObG Project website. During the period from 1/15/2020 through 07/15/2022, participants must read the learning objectives and faculty disclosures and study the educational activity.
If you wish to receive acknowledgment for completing this activity, please complete the post-test and evaluation. Upon registering and successfully completing the post-test with a score of 100% and the activity evaluation, your certificate will be made available immediately.
For Pharmacists: Upon successfully completing the post-test with a score of 100% and the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 4 weeks.
Joint Accreditation Statement
In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and The ObG Project. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physician Continuing Medical Education
Postgraduate Institute for Medicine designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Continuing Nursing Education
The maximum number of hours awarded for this Continuing Nursing Education activity is 0.2 contact hours.
Pancreatic cancer is uncommon but remains the third most common cause of cancer death in the US. The USPSTF predicts that pancreatic cancer may become the 2nd most common cause due to (1) increasing incidence (2) improved detection (3) increased survival from other cancers due to new therapies. The last recommendation on this topic was in 2004 and therefore the USPSTF sought to update guidance based on the latest evidence review
The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults (D recommendation)
The USPSTF does not recommend screening for pancreatic cancer in the general population using any method
Note: Applicable population: Asymptomatic adults not known to be at high risk of pancreatic cancer
Benefits are considered no greater than ‘small’
Pancreatic cancer incidence is low in the general population
age-adjusted annual incidence of 12.9 cases per 100,000 person-years
Accuracy of current candidate screening tests remains uncertain
USPSTF does not recommend screening using “any method”
Pancreatic cancer has a poor prognosis even when treated early
Potential harms are considered at least ‘moderate’
Potential for false-positive results
Consequent harms of treatment: Pancreatectomy carries significant morbidity and mortality
This recommendation does apply to individuals at high risk, e.g., carriers of pathogenic mutations for genetic syndromes or with a significant family history
Potential early detection screening tests were reviewed and were found to be not sufficiently accurate to apply to general populations
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Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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