2018/2019 ACC/AHA Multisociety Guideline on the Management of Blood Cholesterol provides recommendations for the evaluation and prevention of ASCVD. The ‘ASCVD Risk Estimator Plus for Primary Prevention’ link is provided in the ‘Learn More – Primary Sources’ section below.
Algorithm Assessment for Primary Prevention (age 40-75)
LDL-C: <70 mg/dL
LDL-C: 70-189 mg/dL
LDL-C: ≥190 mg/dL (primary severe hypercholesterolemia)
LDL-C: 70-189 mg/dL
Should be discussed and emphasized in each age group
High Intensity (≥50% LDL-C lowering)
Moderate-Intensity (30% to 49% LDL-C lowering)
Low-Intensity (<30% LDL-C lowering)
Note: Repeat lipid measurements and 4 to 12 weeks after starting therapy and assess response as well as lifestyle changes
Statin Associated Muscle Symptoms (SAMS)
New Onset Diabetes
Liver
CNS
Cancer
Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication (2022)
2018 ACC/AHA Multisociety Guideline on the Management of Blood Cholesterol
New Cholesterol Guidelines Personalize Risk and Add Treatments
ASCVD Risk Estimator Plus for Primary Prevention
JAMA Viewpoint: Reexamining Recommendations for Treatment of Hypercholesterolemia in Older Adults
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