Double-Balloon Catheter or Prostaglandin E2 for Cervical Ripening
This study by Du et al. (BJOG, 2017) sought to compare the safety and efficacy of double-balloon catheter and prostaglandin E2 (PGE2) agents for inducing labor.
Systematic Review and Meta-Analysis of Randomized Controlled Trials
Nine studies including 1,866 patients were included in this survey. The primary outcome measure was vaginal delivery rate within 24 hours and C-section risk. There was no statistical difference found between double-balloon catheter and PGE2 agents (relative risk 0.92; 95% CI 0.79-1.07) or vaginal delivery within 24 hours (relative risk 0.95; 95% CI 0.78-1.16). Nor did the investigators find any differences maternal adverse events. However, excessive uterine activity was strongly associated with PGE2 agents (relative risk 10.02; 95% CI 3.99-25.17. In addition, NICU admission rates were also higher in the PGE2 group (relative risk 1.31; 95% CI 1.01-1.69). The authors conclude that while both mechanical and pharmacologic cervical ripening agents are effective, the double-balloon catheter is safer and more cost-effective.
OBG Project CME requires a modern web browser (Internet Explorer 10+, Mozilla Firefox, Apple Safari, Google Chrome, Microsoft Edge). Certain educational activities may require additional software to view multimedia, presentation, or printable versions of their content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Apple QuickTime, Adobe Acrobat, Microsoft PowerPoint, Windows Media Player, or Real Networks Real One Player.
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Jointly provided by
NOT ENOUGH CME HOURS
It appears you don't have enough CME Hours to take this Post-Test. Feel free to buy additional CME hours or upgrade your current CME subscription plan