Actual GDM Risks for Adverse Outcomes Based on a Large Dataset
This study by Billionnet et al. (Diabetologia, 2017) analyzed the link between gestational diabetes mellitus (GDM) and risk of adverse perinatal outcomes.
Retrospective Cohort Study
705,198 mothers, 57,629 with GDM, were surveyed. It was found that the risk of adverse outcomes such as preterm birth, C-section, macrosomia, respiratory distress, birth trauma, and cardiac malformations were all significantly higher in women with GDM and especially pre-eclampsia/eclampsia, with an odds ratio of 1.7 (95% CI 1.6, 1.7). Women with insulin-treated GDM had higher risks than those with diet-treated GDM.
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