This study by Bove et al. (Multiple Sclerosis, 2017) evaluated the relationship between oral contraceptives (OCs) and risk of relapse for women with multiple sclerosis (MS).
Longitudinal observational cohort study
162 women with MS or clinically isolated syndrome (CIS) taking OCs who had begun injectable disease-modifying therapy within two years of diagnoses were studied. The study examined women who currently take OCs, had taken OCs in the past, and those who had never taken OCs. Women who had previously taken OCs had lower rates of relapse than those who had never take OCs. Annualized relapse rate was not significantly different across the three groups of women. Important conclusion based on the data – OC use does not increase risk of MS relapse.
Oral contraceptives and MS disease activity in a contemporary real-world cohort
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