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ACOG Committee Opinion on Delayed Cord Clamping

 

SUMMARY:

For both ‘vigorous’ term and preterm infants, ACOG recommends waiting at delayed clamping the umbilical cord. The committee opinion provides a comprehensive literature and evidence review. ACOG states

In term infants, delayed umbilical cord clamping increases hemoglobin levels at birth and improves iron stores in the first several months of life, which may have a favorable effect on developmental outcomes

Delayed umbilical cord clamping is associated with significant neonatal benefits in preterm infants, including improved transitional circulation, better establishment of red blood cell volume, decreased need for blood transfusion, and lower incidence of necrotizing enterocolitis and intraventricular hemorrhage

Benefits include

  • Term infants
    • Increased hemoglobin levels and iron stores
  • Preterm infants
    • Improved transitional circulation
    • Better establishment of RBC volume
    • Decreased blood transfusion
    • Lower risk of NEC and IVH

Note: There was no evidence for increased risk of PPH

Caution: The committee opinion notes that there may be a small risk for jaundice requiring phototherapy in term infants and therefore the delivery center should have the necessary infrastructure to monitor and treat, if necessary

Duration of Delay

  • Term
    • 30 to 60 seconds 
  • Preterm (See ACOG Update in ‘Learn More – Primary Sources’ below)
    • <37 weeks (no need for immediate resuscitation): ≥60 seconds

Immediate Umbilical Cord Clamping

When is delayed cord clamping not appropriate?

  • Maternal reasons
    • Hemorrhage
    • Hemodynamic instability
    • Abnormal placentation (e.g., previa, abruption etc.)
  • Fetal / Neonatal reasons
    • Need for immediate resuscitation
    • Placental circulation not intact
      • abruption
      • previa
      • cord avulsion
      • IUGR with abnormal cord Doppler

NOTE: ACOG states

Maternal hemodynamic instability or the need for immediate resuscitation of the newborn on the warmer would be an indication for immediate umbilical cord clamping

Cord Milking

  • Based on the latest evidence (see ‘Learn More – Primary Sources’ ACOG Update below)

In preterm neonates born at 28 0/7–36 6/7 weeks of gestation who do not receive deferred cord clamping, umbilical cord milking is a reasonable alternative to immediate cord clamping to improve neonatal hematologic outcomes

Learn More – Primary Sources:

ACOG Committee Opinion 814: Delayed Umbilical Cord Clamping After Birth

ACOG Update to Clinical Guidance for Delayed Umbilical Cord Clamping After Birth in Preterm Neonates