The median within-individual change MAP between high- and low-sodium diets was not impacted by hypertension status
4 mm Hg (IQR, 0 to 8) | P<0.001
46% met criteria met traditional definition of ‘salt sensitive’ based on ≥5 mm Hg change
There was a decrease in within-individual MAP in the majority of participants with lower dietary sodium intake
Low-sodium MAP decline: 73.4%
Mean systolic BP difference between individuals allocated to a high-sodium vs a low-sodium diet
8 mm Hg (95% CI, 4 to 11) | P<0.001
Not statistically different between subgroups
Adverse events were mild
The majority of older adults who lowered dietary sodium experienced a reduction in mean arterial pressure
This decline was not associated with hypertension status or use of antihypertensive medication
The authors state
That none of the classes of antihypertensive medications was consistently associated with the BP response to dietary sodium emphasizes the importance of continued lifestyle modification even among individuals with treated hypertension
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