Sepsis accounts for about 14% of all pregnancy-related deaths despite occurring in only 4 per 10,000 live births, and the rate of maternal sepsis appears to be increasing. More than 50% of pregnant patients who die from sepsis have at least one chronic comorbidity, such as congestive heart failure or chronic renal disease. The diagnosis of sepsis in the early postpartum period can be difficult due to the rapid physiologic changes that occur postpartum, such as large fluid shifts, postpartum hemorrhage, and heart rate and blood pressure alterations. This consult series document refers to sepsis in individuals who are either pregnant or in the postpartum period.
Note: No source identified in 30% of cases
Note: Low sensitivity and has not been validated in pregnancy
Initial Management: within the first hour of suspected diagnosis
Proposed Antibiotic Coverage Based on Source
Vasopressors and Inotropes
When to Deliver
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