Ovarian endometrioma (OMA; potentially associated with SUP)
Deep endometriosis (DE; potentially associated with SUP and OMA)
Control: No clinical endometriosis symptoms
Association between endometriosis and the primary outcome was assessed through univariate and multivariate logistic regression analyses
Adjusted for preterm risk factors
Maternal age | BMI before pregnancy | Country of birth | Parity | Previous cesarean delivery | History of myomectomy and hysteroscopy, and preterm birth
The same analysis was performed according to the 3 endometriosis phenotypes
Preterm birth between 22w0d and 36w6d
1351 study participants
Mean (SD) age 32.9 (5.0) years
Endometriosis diagnosis: 470 participants
There was no difference in the rate of preterm birth between groups
After adjustment, endometriosis was still not associated with preterm birth
aOR 1.07 (95% CI, 0.64 to 1.77)
Results were comparable across different disease phenotypes (P=0.84)
SUP: 6.2% preterm birth
OMA: 7.2% preterm birth
DE: 7.4% preterm birth
In this cohort, there was no association between endometriosis and incidence of preterm birth
Endometriosis phenotype did not modify this finding
The authors state
Pregnant women with endometriosis should not be considered to have an exceptionally high risk for preterm birth; thus, monitoring their pregnancy beyond the normal protocols or changing management strategies may not be warranted
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