Mor et al. (Fertility and Sterility, 2021) sought to determine if a high AFP level in vaginal blood collected on pads could serve as a reliable marker for incomplete or missed miscarriage with first trimester bleeding
Prospective cohort study
Pregnant women with vaginal bleeding
Women undergoing elective D&C as a positive control
Active miscarriage (missed or incomplete)
Pregnancy of unknown location (PUL)
Completed miscarriage or extrauterine pregnancy (EUP)
AFP levels calculated
Sensitivity & specificity, and receiver operating characteristic (ROC) were calculated
Performance of AFP for detection of miscarriage
Women with vaginal bleeding: 76 | Women undergoing D&C: 24
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