Primary Outcome: Menstrual blood loss <80 ml and a ≥50% reduction in volume from baseline
In these trials, once-daily relugolix combination therapy resulted in a substantial reduction in heavy menstrual bleeding in women with uterine fibroids, with resolution of anemia, a reduction in pain, and reduced distress related to bleeding and pelvic discomfort, while preserving bone density and minimizing the incidence of hot flashes associated with relugolix monotherapy
Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy
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