• About Us
    • Contact Us
    • Login
    • ObGFirst
  • COVID-19
  • Alerts
  • OB
  • 2T US Atlas
  • The Genome
  • GYN
    • GYN
    • Sexual Health
  • Primary Care
  • Your Practice
  • #GrandRounds
  • My Bookshelf
  • Now@ObG
  • Media
About Us Contact Us Login ObGFirst
  • COVID-19
  • Alerts
  • OB
  • 2T US Atlas
  • The Genome
  • GYN
    • 0 CME Hours
    • GYN
    • Sexual Health
  • Primary Care
  • Your Practice
  • #GrandRounds
  • My Bookshelf
  • Now@ObG
  • Media
#Grand Rounds

A New Intrauterine Device to Treat Postpartum Hemorrhage

image_pdfFavoriteLoadingFavorite

BACKGROUND AND PURPOSE:

  • A new device has been developed that can apply low-level intrauterine vacuum (70–90 mm Hg) to facilitate uterine contractions and constrict blood vessels
  • D’Alton et al. (Obstetrics & Gynecology, 2020) evaluated the effectiveness and safety of this device to treat PPH

METHODS:

  • Multicenter, prospective, single-arm treatment study
  • Participants
    • Delivery ≥34 weeks
    • Normal uterine anatomy
    • Atony-related blood loss
      • Vaginal delivery: 500 to 1,500 mL
      • Cesarean: 1,000–1,500 mL
    • Unresponsive to uterotonics and uterine massage
  • Intervention
    • Intrauterine vacuum device
  • Primary effectiveness outcome
    • Proportion of participants treated with intrauterine vacuum device that did not require escalating interventions
  • Primary endpoints
    • Device-related adverse events
      • Incidence | Severity | Seriousness
  • Secondary endpoints
    • Time to bleeding control
    • Rate of transfusion
    • Device usability scored by each practitioner

RESULTS:

  • 106 participants
  • Successful treatment: 94% (95% CI, 88 to 98%)
    • Median time to control: 3 minutes (IQR 2.0 to 5.0 min)
  • Adverse events related to the device
    • 8 events
    • All were outlined as risks in the study
    • All were resolved without serious clinical sequelae
    • Adverse events included
      • Endometritis | Disruption of vaginal laceration repair | Presumed endometritis | Bacterial vaginosis | Vaginal candidiasis
  • Transfusions
    • 1 to 3 units: 33%
    • ≥4 units: 5%
  • Ease of use
    • Reported ease of use: 98%
    • Reported would recommend it: 97%

CONCLUSION:

  • Among successfully treated patients, control of abnormal bleeding was quickly established
  • The authors state that while an RCT should be considered in the future, the device

…offers a therapeutic modality that may be considered early in the treatment of abnormal postpartum uterine bleeding or postpartum hemorrhage

Learn More – Primary Sources:

Intrauterine Vacuum-Induced Hemorrhage-Control Device for Rapid Treatment of Postpartum Hemorrhage

Now You Can Get ObG Clinical Research Summaries Direct to Your Phone, with ObGFirst

ObGFirst® – Try It Free! »

image_pdfFavoriteLoadingFavorite
< Previous
All #Grand Rounds Posts
Next >

Related ObG Topics:

How Effective is Intrauterine Balloon Tamponade for Severe Postpartum Hemorrhage
Does Prophylactic TXA Reduce Postpartum Hemorrhage?
Results From the Landmark Trial on Tranexamic Acid for Postpartum Hemorrhage

Sections

  • COVID-19
  • Alerts
  • OB
  • GYN
    • GYN
    • Sexual Health
  • 2T US Atlas
  • The Genome
  • Primary Care
  • Your Practice
  • #Grand Rounds
  • My Bookshelf
  • Now@ObG
  • Media

ObG Library

  • Hysteroscopy
  • Fertility
  • Site Map/
  • © ObG Project/
  • Terms and Conditions/
  • Privacy/
  • Contact Us/
© ObG Project
SSL Certificate


  • Already an ObGFirst Member?
    Welcome back

    Log In

    Want to sign up?
    Get guideline notifications
    CME Included

    Sign Up

Get Guideline Alerts Direct to Your Phone
Try ObGFirst Free!

Sign In

Lost your password?

Sign Up for ObGFirst and Stay Ahead

  • - Professional guideline notifications
  • - Daily summary of a clinically relevant
    research paper
  • - Includes 1 hour of CME every month

ObGFirst Free Trial

Log In to ObG First

Please log in to access OBGFirst and the 2T Ultrasound Atlas

Password Trouble?

Sign Up for ObGFirst

  • - Access 2T US Atlas
  • - Guideline notifications
  • - Daily research paper summaries
  • - And lots more!

ObG First Free Trial

Media - Internet

Computer System Requirements

OBG Project CME requires a modern web browser (Internet Explorer 10+, Mozilla Firefox, Apple Safari, Google Chrome, Microsoft Edge). Certain educational activities may require additional software to view multimedia, presentation, or printable versions of their content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Apple QuickTime, Adobe Acrobat, Microsoft PowerPoint, Windows Media Player, or Real Networks Real One Player.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Jointly provided by

NOT ENOUGH CME HOURS

It appears you don't have enough CME Hours to take this Post-Test. Feel free to buy additional CME hours or upgrade your current CME subscription plan

Subscribe

JOIN OBGFIRST AND GET CME/CE CREDITS

One of the benefits of an ObGFirst subscription is the ability to earn CME/CE credits from the ObG entries you read. Tap the button to learn more about ObGFirst

Learn More
Leaving ObG Website

You are now leaving the ObG website and on your way to PRIORITY at UCSF, an independent website. Therefore, we are not responsible for the content or availability of this site