Hysterectomy (indication for (pre‐)malignant polyp pathology result for the polyp: 50 cases
Atypical hyperplasia confined to polyp: 35 cases
Endometrial carcinoma confined to the polyp: 15 cases
Endometrial histopathology among the 35 women with atypical hyperplasia confined to the polyp
No additional pre-malignant changes in the endometrium: 30.8% (12 women)
Atypical hyperplasia: 28.2% (11 women)
Endometrial carcinoma: 30.8% (12 women)
Older age, postmenopausal status, tamoxifen use or bleeding at presentation were not associated with whether a polyp had (pre‐)malignant changes
Endometrial carcinoma was found in 30.8% of hysterectomy specimens performed for atypical hyperplasia confined to a polyp
The authors conclude that the data in this study supports a recommendation “to perform a hysterectomy and bilateral salpingo-oophorectomy for polyps with confined atypical hyperplasia in postmenopause and surgery or progestogens in premenopausal women”
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