ACOG has published a Practice Bulletin (April 2020) that provides guidance on the use of antibiotics in the setting of operative vaginal delivery. The recommendations follow the publication of the ANODE RCT that demonstrated antibiotic prophylaxis reduces the risk of maternal infection following operative vaginal birth. The authors of this trial concluded that “this trial shows clear benefit of a single dose of prophylactic antibiotic after operative vaginal birth, and guidance should be changed to reflect this finding”
Background and Purpose
Methods
Results
…use of routine prophylactic antibiotics before delivery would not be recommended. Because wound infections and complications are more common in the setting of a third- or fourth-degree laceration, it may be more judicious to consider antibiotics if a third- or fourth-degree laceration occurs”
ACOG Practice Bulletin 219: Operative Vaginal Birth
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