While most children will be asymptomatic or exhibit mild symptoms, SARS-CoV-2 infection has been temporally associated with a syndrome called Pediatric Multi-System Inflammatory Syndrome. It was first identified in the UK and cases have now been reported in New York City, a US ‘hot spot’ for COVID-19. The underlying mechanism for this severe inflammatory syndrome is not yet understood, but some speculate that the antibody following illness may be generating an overly vigorous immune response in these children and teens.
Note: Royal College of Paediatrics and Child Health (RCPCH) Guidelines (see ‘Learn More – Primary Sources’) provide a comprehensive list of symptoms as well as clinical, laboratory and imaging findings
The RCPCH expert panel add that
It’s very important to keep this in perspective. It’s a very rare condition and because of that parents shouldn’t be alarmed. We’re talking about a really small number of cases, each of which was picked up and treated by experts in our health system. It remains extremely unlikely that a child will become unwell with COVID-19, and it’s even more unlikely that a child will become unwell with this condition. I want to reassure parents that our advice to them has not changed. If you have an unwell child, it probably isn’t anything to do with COVID and is more likely to be something else. If you’re concerned, do what you’d normally do. Call your GP, use NHS 111, or for emergencies – go to hospital
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