Does the Presence of Ovarian Dermoid Cysts Impact IVF Success?
BACKGROUND AND PURPOSE:
It is unclear if treatment of dermoid cysts may
impair fertility treatment due to potential negative impact on ovarian reserve
Hernandez-Nieto et al. (International Journal of
Obstetrics and Gynecology, 2019) assessed IVF treatment success among women
with intact dermoid cysts and those with history of resection vs a control
Women with ovarian dermoid cysts (confirmed with ultrasound) undergoing IVF with fresh blastocyst transfer
Control group: No dermoid cysts
Multivariate logistic regression was used to assess associations between variables and the presence of a dermoid cyst during treatment
119 women with dermoid cysts | Control group:
Conservative management (no surgery): 54.6%
Overall, no demographic differences between
groups | There was a significant difference in cyst size between those with intact
vs resected (1.9 ± 1.6 cm vs 4.1 ± 2.3 cm; P<0.001)
There were no differences in the following
between the two dermoid cyst groups
Controlled ovarian hyperstimulation parameters
Compared to the control group, there was no
difference in AMH levels
Comparing women with conservative vs surgical
treatment for dermoid cysts, there was no difference in basal antral follicle
IVF was just as successful for women with
dermoid cysts (managed conservatively or with surgery) as it was for those
women without dermoid cysts
The authors suggest that based on the results of
this study, surgical removal could be safely postponed until after fertility
treatment | For those who opt for surgery, excision did not impact outcomes
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This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
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presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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