Opportunistic Salpingectomy: A Surgical Approach to Reducing Ovarian Cancer Risk
ACOG addresses the role of opportunistic salpingectomy in reducing ovarian cancer risk for women undergoing hysterectomy (benign conditions) or cesarean section. The recommendations apply to women at average ‘population’ risk for ovarian cancer and not those at high risk (for example BRCA mutation carriers). Risks and benefits should be discussed with women considering opportunistic salpingectomy.
Science Behind the Guidance
“Strong” data suggests that ovarian cancers (including serous, endometrioid, and clear cell) derive from endometrium or fallopian tube and not ovary itself
Therefore, bilateral salpingectomy at time of hysterectomy or cesarean, even if ovaries are left in situ, should reduce ovarian cancer risk
Note: Even if the above is correct, some ovarian cancers will arise from the ovary, not the tube | Opportunistic salpingectomy should not be considered 100% preventative
Risks Associated with Opportunistic Salpingectomy
The following complications have not been demonstrated in women undergoing opportunistic salpingectomy
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This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
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presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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