Results from the FluMum Study: Flu and Pertussis Vaccine Safety
BACKGROUND AND PURPOSE:
McHugh et al. (Clinical Infectious Diseases, 2019) sought to determine whether vaccination with inactivated influenza vaccine (IIV) and pertussis vaccination during pregnancy, particularly in the first trimester, increased risk for adverse birth outcomes
Prospective cohort study
Patients had received IIV during pregnancy
Primary outcomes compared to unvaccinated women
Preterm birth (<37 weeks) | Low birthweight at term (LBWT, <2500g) | SGA
Associations between IIV and adverse outcomes were adjusted based on administration of pertussis vaccine
Additional data collected to assess confounding included
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Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
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