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OB
CMECNE

The Role of Routine Cervical Length Screening For Preterm Birth Prevention

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Learning Objectives and CME/Disclosure Information

This activity is intended for healthcare providers delivering care to women and their families.

After completing this activity, the participant should be better able to:

1. Perform a cervical length assessment in pregnancy
2. Discuss the timing of cervical length screening or surveillance in pregnancy

Estimated time to complete activity: 0.25 hours

Faculty:

Susan J. Gross, MD, FRCSC, FACOG, FACMG President and CEO, The ObG Project

Disclosure of Conflicts of Interest

Postgraduate Institute for Medicine (PIM) requires faculty, planners, and others in control of educational content to disclose all their financial relationships with ineligible companies. All identified conflicts of interest (COI) are thoroughly vetted and mitigated according to PIM policy. PIM is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.


The PIM planners and others have nothing to disclose. The OBG Project planners and others have nothing to disclose.

Faculty: Susan J. Gross, MD, receives consulting fees from Cradle Genomics, and has financial interest in The ObG Project, Inc.

Planners and Managers: The PIM planners and managers, Trace Hutchison, PharmD, Samantha Mattiucci, PharmD, CHCP, Judi Smelker-Mitchek, MBA, MSN, RN, and Jan Schultz, MSN, RN, CHCP have nothing to disclose.

Method of Participation and Request for Credit

Fees for participating and receiving CME credit for this activity are as posted on The ObG Project website. During the period from August 7 2018 through Jan 25 2023, participants must read the learning objectives and faculty disclosures and study the educational activity.

If you wish to receive acknowledgment for completing this activity, please complete the post-test and evaluation. Upon registering and successfully completing the post-test with a score of 100% and the activity evaluation, your certificate will be made available immediately.

For Pharmacists: Upon successfully completing the post-test with a score of 100% and the activity evaluation form, transcript information will be sent to the NABP CPE Monitor Service within 4 weeks.

Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and The ObG Project. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education

Postgraduate Institute for Medicine designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Continuing Nursing Education

The maximum number of hours awarded for this Continuing Nursing Education activity is 0.2 contact hours.

Read Disclaimer & Fine Print

CLINICAL ACTIONS:

SMFM and other professional organizations have released guidance on cervical length (CL) screening for preterm birth (PTB) prevention. The finding of a short cervix, irrespective of obstetric history, has been consistently shown to be associated with higher risk for PTB.

Steps for CL assessment

  • Have patient empty bladder
  • Acquire the sagittal, long-axis image of entire cervix (75% of screen)
  • Confirm that the anterior and posterior cervixes are of equal thickness
  • Measure endocervical canal from internal to external os
    • Ensure that internal and external os are seen and canal seen throughout
    • Place calipers at the internal and external os where the anterior and posterior walls of the cervix meet
  • If the endocervical canal curves
    • Add linear measurements together to obtain the final cervical length
  • Dynamic cervical shortening
    • Exam time 3–5 minutes and/or
    • suprapubic/fundal pressure
  • Obtain 3 images for CL determination
    • Use the shortest, best measurement

Note: SMFM does not recommend routine CL surveillance in women with cerclage, multiple gestation, PPROM, or placenta previa (Grade 2B)

Who and When to Screen for CL

Screening in Asymptomatic women

  • SMFM
    • Based on evidence, general population screening “cannot yet be universally mandated”
    • For those who wish to screen their patients including low risk, it may be considered ‘reasonable’ with
      • “Strict adherence to guidelines”
      • Measurement between 16 and 24 weeks (Grade 2B)
  • SOGC (Canada)
    • Universal screening in Canada can not be mandated at this time and more research is warranted
  • ISUOG
    • Insufficient evidence to recommend offering universal screening in the general population
  • RANZCOG
    • Cervical length measurement at 18-24 weeks should be “considered”
    • Two step approach of abdominal scan first followed by transvaginal as needed
  • FIGO
    • Does recommend measurement in low risk population
    • “Should be performed in all pregnant women at 19–23+6 weeks of gestation using transvaginal ultrasound”
    • Can be done same time as anatomic scan

Surveillance in asymptomatic women with prior sPTB

  • SMFM: Every 1 to 2 weeks (depending on clinical status) between 16 and 24 weeks (Grade 1A)

SYNOPSIS:

Two thirds of preterm births are spontaneous, and only 10% of births <34 weeks will occur to women with a history of spontaneous preterm birth (sPTB). Few predictive tests are available for PTB prediction, and mid-trimester CL assessment remains the best clinical tool at identifying high-risk women. Women with short cervix and prior sPTB are at highest risk.

KEY POINTS:

  • Current threshold for “short” cervix: Range of 20 to 30 mm
  • Transvaginal ultrasound is more sensitive and reproducible that transabdominal ultrasound in detecting cervical shortening
  • Sonographers and practitioners should receive specific training in acquisition and interpretation of cervical imaging (Grade 2B)
  • Practitioners who implement universal screening should follow strict guidelines (Grade 2B)

Special circumstances

  • History of treatment for cervical dysplasia (LEEP, cold-knife cone)
    • CL screening the same as that of asymptomatic women without history of sPTB
  • Determining status post-cerclage placement
    • Insufficient data to suggest clinical benefit (Grade 2B)
  • Multiple gestations
    • 18% will have short cervix by 22-24 weeks
    • SMFM does not recommend CL surveillance due to lack of effective interventions (Grade 2B)
  • Threatened preterm labor (PTL)
    • CL measurement may be used as adjunct to digital examination
    • In conjunction with FFN in women with CL of 20-29 mm (‘grey zone’)
      • FFN negative: no treatment
      • FFN positive: corticosteroids and additional interventions
    • PPROM
      • Insufficient data to suggest clinical benefit (Grade 2B)
    • Placenta previa
      • Insufficient data to suggest clinical benefit (Grade 2B)

Learn More – Primary Sources:

SMFM Consult Series #40: The role of routine cervical length screening in selected high-and low-risk women for preterm birth prevention

AIUM Practice Parameter for the Performance of Limited Obstetric Ultrasound Examinations by Advanced Clinical Providers

Fetal Medicine Foundation Cervical Length Assessment Program

SOGC: Universal Cervical Length Screening

FIGO: Best Practices in Maternal Fetal Medicine 

ISUOG: How to Measure Cervical Length

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Related ObG Topics:

Does fetal fibronectin testing prevent preterm birth?
Does Shortened Midtrimester Cervical Length Predict Preterm Birth?
Does Vaginal Progesterone Improve Birth Outcomes for Mothers with Short Cervix?
Cervical Cerclage – Professional Recommendations

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Computer System Requirements

OBG Project CME requires a modern web browser (Internet Explorer 10+, Mozilla Firefox, Apple Safari, Google Chrome, Microsoft Edge). Certain educational activities may require additional software to view multimedia, presentation, or printable versions of their content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Apple QuickTime, Adobe Acrobat, Microsoft PowerPoint, Windows Media Player, or Real Networks Real One Player.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

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