Benefits of IUDs include lower endometrial cancer incidence (non-hormonal)
Cortessis et al. (Obstetrics & Gynecology, 2017) examined the association between IUDs and cervical cancer risk
Systematic review and meta-analysis
34 studies with individual-level measures of use of an IUD and incident cervical cancer
17 studies following initial review for systematic error and 16 were included in the meta-analysis
Women who used IUDs had a reduced risk for cervical cancer (summary odds ratio [OR] 0.64, 95% CI 0.53–0.77)
Study could not look more specifically at hormonal vs nonhormonal IUD, duration of use, or age at placement
Invasive cervical cancer may be approximately 30% less frequent in women who have used an IUD
This possible noncontraceptive benefit could be most beneficial in populations with severely limited access to screening and concomitantly high cervical cancer incidence
This protective mechanism is currently unknown, but authors suggest it may have to do with an immune response to cervical manipulation required for placement or simply a more chronic response to presence of the IUD
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