• About Us
    • Contact Us
    • Login
    • ObGFirst
  • COVID-19
  • Alerts
  • OB
  • 2T US Atlas
  • The Genome
  • GYN
    • GYN
    • Sexual Health
  • Primary Care
  • Your Practice
  • #GrandRounds
  • My Bookshelf
  • Now@ObG
  • Media
About Us Contact Us Login ObGFirst
  • COVID-19
  • Alerts
  • OB
  • 2T US Atlas
  • The Genome
  • GYN
    • 0 CME Hours
    • GYN
    • Sexual Health
  • Primary Care
  • Your Practice
  • #GrandRounds
  • My Bookshelf
  • Now@ObG
  • Media
#Grand Rounds

What are the Risk Factors Associated with Endometrial Ablation?

image_pdfFavoriteLoadingFavorite

BACKGROUND AND PURPOSE:

  • No population-based studies on the effect of new endometrial ablation techniques on endometrial cancer exist
  • Also unknown is whether heavy menstrual bleeding is associated with increased risk for breast cancer
  • Soini et al. (Obstetrics & Gynecology, 2017) sought to determine endometrial and breast cancer rates post-ablation, as well as future hysterectomy rates

METHODS:

  • Observational, retrospective nationwide cohort (Finland; 1997-2014)
  • Women 30-49 years of age who underwent endometrial ablation
  • Primary outcome was cancer rates in the ablation cohort versus control cohort
  • Post-ablation hysterectomy rates were also compared between ablation and control cohorts as a secondary outcome

RESULTS:

  • Final study cohort included 5484 women in the ablation group and 26,938 in the control group
  • 154 total cancer incidence were recorded within ~39,000 women/years of patients with endometrial ablation
  • The standardized incidence for cancers was not statistically increased in the ablation group
    • The standardized incidence ratio for endometrial cancer was 0.56 (95% CI 0.12–1.64; three observed compared with five expected cases)
    • The standardized incidence ratio for breast cancer was 0.86 (95% CI 0.67–1.09; 67 observed compared with 78 expected cases)
  • Risk of hysterectomy was almost four-fold higher in the ablation cohort
  • Factors predisposing to postablation hysterectomy were
    • Leiomyomas
    • Age younger than 35 y/o
    • At least two prior cesarean deliveries
    • History of sterilization

CONCLUSION:

  • Women with endometrial ablation were not at a higher risk for breast or endometrial cancer
  • There was a higher risk of hysterectomy due to higher rates of risk factors listed above
  • Authors state a limitation of study is that the type of ablation devices were not available, but there are no differences in effectiveness among various devices

Learn More – Primary Sources:

Long-term Follow-up After Endometrial Ablation in Finland: Cancer Risks and Later Hysterectomies.

image_pdfFavoriteLoadingFavorite

< Previous
All #Grand Rounds Posts
Next >

Related ObG Topics:

Endometrial Ablation – When is This Procedure Appropriate?
Laparoscopic Excision vs. Ablation for Treating Endometriosis-Associated Pain
IUD, Hysterectomy or Ablation for Menorrhagia?

Sections

  • COVID-19
  • Alerts
  • OB
  • GYN
    • GYN
    • Sexual Health
  • 2T US Atlas
  • The Genome
  • Primary Care
  • Your Practice
  • #Grand Rounds
  • My Bookshelf
  • Now@ObG
  • Media

ObG Library

  • Hysteroscopy
  • Fertility
  • Site Map/
  • © ObG Project/
  • Terms and Conditions/
  • Privacy/
  • Contact Us/
© ObG Project
SSL Certificate


  • Already an ObGFirst Member?
    Welcome back

    Log In

    Want to sign up?
    Get guideline notifications
    CME Included

    Sign Up

Get Guideline Alerts Direct to Your Phone
Try ObGFirst Free!

Sign In

Lost your password?

Sign Up for ObGFirst and Stay Ahead

  • - Professional guideline notifications
  • - Daily summary of a clinically relevant
    research paper
  • - Includes 1 hour of CME every month

ObGFirst Free Trial

Log In to ObG First

Please log in to access OBGFirst and the 2T Ultrasound Atlas

Password Trouble?

Sign Up for ObGFirst

  • - Access 2T US Atlas
  • - Guideline notifications
  • - Daily research paper summaries
  • - And lots more!

ObG First Free Trial

Media - Internet

Computer System Requirements

OBG Project CME requires a modern web browser (Internet Explorer 10+, Mozilla Firefox, Apple Safari, Google Chrome, Microsoft Edge). Certain educational activities may require additional software to view multimedia, presentation, or printable versions of their content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Apple QuickTime, Adobe Acrobat, Microsoft PowerPoint, Windows Media Player, or Real Networks Real One Player.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Jointly provided by

NOT ENOUGH CME HOURS

It appears you don't have enough CME Hours to take this Post-Test. Feel free to buy additional CME hours or upgrade your current CME subscription plan

Subscribe

JOIN OBGFIRST AND GET CME/CE CREDITS

One of the benefits of an ObGFirst subscription is the ability to earn CME/CE credits from the ObG entries you read. Tap the button to learn more about ObGFirst

Learn More
Leaving ObG Website

You are now leaving the ObG website and on your way to PRIORITY at UCSF, an independent website. Therefore, we are not responsible for the content or availability of this site