Is the DASH Diet Effective for Obese Women with PCOS?
BACKGROUND AND PURPOSE:
Management of BMI and weight reduction is an important component of the management plan for PCOS.
The Dietary Approaches to Stop Hypertension (DASH) diet (see ‘Primary Sources for more information) is used to treat obesity and high blood pressure
This study by Azadi-Yazdi et al. (Journal of Human Nutrition and Diet, 2017) sought to determine the effects of the DASH diet on reproductive hormones, plasma total antioxidant status, and anthropometric indices in overweight and obese women with PCOS
Randomized Controlled Trial (RCT)
60 overweight (BMI 25-29 kg m2) and obese (BMI ≥ 30 kg m2) women with PCOS were randomized to a either DASH or control diet
Both diets consisted of 50-55% carbohydrates, 15-20% protein, and 25-30% total fat
The DASH diet is rich in vegetables, fruits, whole grains, and low-fat dairy product and low in saturated fats, cholesterol, refine grains, and sugars
Outcomes measures were obtained before and 3 months after diet included
Primary outcome: difference in testosterone
Secondary outcomes: differences in androstenedione and SHBG, body composition and total antioxidant capacity
Weight loss was greater on the DASH diet (-5.78 kg versus -4.34, P = 0.032)
Drop in BMI was greater on the DASH diet (-2.29 kg m-2 versus -1.69 kg m-2, P = 0.02)
Decrease in fat mass was greater on the DASH diet (-3.23 kg versus -2.13 kg, P = 0.008)
Drop in serum androstenedione on the DASH diet (-1.75 ng mL-1 versus -1.02 ng mL-1, P-value = 0.019)
SHBG levels were greater on the DASH diet (28.80 versus 11.66 nmol L-1, P = 0.003)
DPPH scavenging activity (antioxidant capacity) was greater in the DASH diet (30.23% versus 12.97%, P = 0.005)
The DASH diet can help with weight loss, lowering BMI, and decreasing fat mass
The DASH diet decreased levels of serum androstenedione
The DASH diet increased antioxidant status and SHBG
For overweight and obese women with PCOS, the DASH diet is an effective way of losing weight and helping hormone levels
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