Does Maternal Hyperemesis Gravidarum Affect Health in Offspring?
This study by Koot et al. (BJOG, 2017) aimed to determine if prenatal exposure to maternal hyperemesis gravidarum (HG) affects the long-term cardiometabolic health of the offspring.
Prospective follow-up of the Northern Finland Birth Cohort 1986
6,462 adolescents were followed up at 16 years of age, 42 of whom had mothers hospitalized for HG due to severe nausea and vomiting compared to 6,420 who did not have mothers with HG. All the adolescents underwent anthropometric measurements, and 36 of the offspring of HG mothers and 5,612 of the offspring of control mothers had fasting blood samples taken. No differences in BMI, blood pressure, fasting glucose, and lipid levels were seen between the two groups of offspring. The authors conclude that at 16 years of age, no evidence of adverse cardiometabolic health outcomes were seen in women who had HG.
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