The appropriate use of antenatal corticosteroids improves neonatal outcomes, including decreased severity and/or frequency of respiratory distress syndrome (RDS), intracranial hemorrhage, necrotizing enterocolitis and death. Antenatal corticosteroids, when appropriate, are administered in a clinical setting where patients are at risk for preterm delivery within 7 days, irrespective of membrane status and fetal number.
Between 24w0d to 33w6d – ‘Recommended’
Between 23w0d and 23w6d – ‘May be Considered’
Note: ACOG and SMFM revised recommendation states
Antenatal corticosteroids may be considered at 22 0/7 weeks to 22 6/7 weeks of gestation if neonatal resuscitation is planned and after appropriate counseling
Some families may choose to forgo resuscitation and support after appropriate counseling
Between 20w0d and 21w6d – ‘Not Recommended’
ACOG
SMFM
ACOG Committee Opinion 713: Antenatal Corticosteroid Therapy for Fetal Maturation
ACOG Practice Advisory: Use of Antenatal Corticosteroids at 22 Weeks of Gestation
ACOG Practice Bulletin No. 171 : Management of Preterm Labor
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