Gastroesophageal reflux disease (GERD) is a chronic condition characterized by the recurrent regurgitation of acidic stomach contents into the esophagus, and/or more proximally, due to a decrease in tone or inappropriate relaxation of the lower esophageal sphincter. GERD has been estimated to occur in 20% of the population of high-income countries. This condition may be diagnosed in association with classical symptoms or following recognition of GERD-related complications.
Symptoms of GERD may be limited to the esophagus and GI tract (typical GERD) and/or may be extra-esophageal
Will occur with or rarely without typical GERD symptoms | Silent GERD is an unlikely diagnosis
Note: Population studies suggest that there is an inverse relationship between H. pylori and GERD | Hypothesis is that H. pylori may associated with decreased acid production and eradication of the pathogen may exacerbate GERD due to increased risk of esophagitis
Medication: Proton Pump Inhibitors (PPIs)
Note: Monitor patient response | If symptoms persist or there is weight loss after initial treatment refer to GI for further evaluation | Further evaluation may include manometric testing or endoscopy | Weight loss, dysphagia or bleeding may suggest malignancy
Get Guideline Alerts Direct to Your Phone
Please log in to ObGFirst to access the 2T US Atlas
OBG Project CME requires a modern web browser (Internet Explorer 10+, Mozilla Firefox, Apple Safari, Google Chrome, Microsoft Edge). Certain educational activities may require additional software to view multimedia, presentation, or printable versions of their content. These activities will be marked as such and will provide links to the required software. That software may be: Adobe Flash, Apple QuickTime, Adobe Acrobat, Microsoft PowerPoint, Windows Media Player, or Real Networks Real One Player.
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information
presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
One of the benefits of an ObGFirst subscription is the ability to earn CME/CE credits from the ObG entries you read. Tap the button to learn more about ObGFirst
You are now leaving the ObG website and on your way to PRIORITY at UCSF, an independent website. Therefore, we are not responsible for the content or availability of this site